After his opening standup, George showed what happened when he went to the midnight premiere of "New Moon" and asked the fans to "make me like it!" The movie's breakout star, Taylor Lautner, sat down to chat with George about "Twilight." They talked about their work together in "Valentine's Day," and how Taylor used to come to George's house trick-or-treating as a kid. Meanwhile, the screaming girls in the audience gave Beatlemania a run for its money. Queen of "The Hills" Kristin Cavallari stopped by to show a clip from the distant future: "The Hills: 2012." George made a surprise visit to a family in need, who had gone broke paying for their daughter's kidney transplant. George arranged for Boost Mobile to give the family $25,000, plus cell phones with free service for an entire year. And if that wasn't enough show for you, LMFAO took the stage and jammed "La, La, La" to close the show!

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Happy Thanksgiving!